Description
CD3 consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta). The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). It is involved in signal transduction to the T cell interior following antigen recognition. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
